Structure based in-silico study on UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-2,6-diaminopimelate ligase (MurE) from Acinetobacter baumannii as a drug target against nosocomial infections
UDP-N-acetylmuramoyl-L-alanyl-d-glutamate--2,6-diaminopimelate ligase (MurE) initiates reaction by adding meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-d-glutamate, during the synthesis of murein in the cytoplasm. This enzyme is crucial for microorganisms includi...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2019-01-01
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| Series: | Informatics in Medicine Unlocked |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352914819301066 |