Graft-Specific Regulatory T Cells for Long-Lasting, Local Tolerance Induction

Graft-Specific Regulatory T Cells for Long-Lasting, Local Tolerance Induction

Background: Solid organ transplantation is hindered by immune-mediated chronic graft dysfunction and the side effects of immunosuppressive therapy. Regulatory T cells (Tregs) are crucial for modulating immune responses post-transplantation; however, the transfer of polyspecific Tregs alone is insuff...

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Bibliografiska uppgifter
Huvudupphovsmän: Nadja Seltrecht, Matthias Hardtke-Wolenski, Konstantinos Iordanidis, Danny Jonigk, Melanie Galla, Axel Schambach, Laura Elisa Buitrago-Molina, Heiner Wedemeyer, Fatih Noyan, Elmar Jaeckel
Materialtyp: Artikel
Språk:English
Publicerad: MDPI AG 2024-07-01
Serie:Cells
Ämnen:
solid organ transplantation
regulatory T cells
alloantigen-specific
immune tolerance
Länkar:https://www.mdpi.com/2073-4409/13/14/1216

Internet

https://www.mdpi.com/2073-4409/13/14/1216

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