Landscape of genomic alterations in high-grade serous ovarian cancer from exceptional long- and short-term survivors

Landscape of genomic alterations in high-grade serous ovarian cancer from exceptional long- and short-term survivors

Abstract Background Patients diagnosed with high-grade serous ovarian cancer (HGSOC) who received initial debulking surgery followed by platinum-based chemotherapy can experience highly variable clinical responses. A small percentage of women experience exceptional long-term survival (long term (LT)...

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Bibliographic Details
Main Authors: S. Y. Cindy Yang, Stephanie Lheureux, Katherine Karakasis, Julia V. Burnier, Jeffery P. Bruce, Derek L. Clouthier, Arnavaz Danesh, Rene Quevedo, Mark Dowar, Youstina Hanna, Tiantian Li, Lin Lu, Wei Xu, Blaise A. Clarke, Pamela S. Ohashi, Patricia A. Shaw, Trevor J. Pugh, Amit M. Oza
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Genome Medicine
Subjects:
Ovarian cancer
Immuno-genomics
Tumor microenvironment
Online Access:http://link.springer.com/article/10.1186/s13073-018-0590-x

Internet

http://link.springer.com/article/10.1186/s13073-018-0590-x

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