Distinct carbapenems susceptibility profiles in isogenic isolates of Klebsiella pneumoniae presenting Ompk36 disruption and expression of down-regulated blaKPC-2

Distinct carbapenems susceptibility profiles in isogenic isolates of Klebsiella pneumoniae presenting Ompk36 disruption and expression of down-regulated blaKPC-2

Abstract The isolation of multidrug-resistant Klebsiella pneumoniae in hospitals is a major public health threat, increasing patient hospitalization costs, morbidity and mortality. Therefore, this work investigated the resistance mechanisms that produced different carbapenems susceptibility profiles...

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Bibliographic Details
Main Authors: P. M. S. Souza, A. C. O. A. Ribeiro, E. P. N. Pena, F. A. C. Silva, T. Calsa Júnior, M. M. C. Morais, A. C. S. Almeida
Format: Article
Language:English
Published: Instituto Internacional de Ecologia 2023-06-01
Series:Brazilian Journal of Biology
Subjects:
bacterial outer membrane proteins
antimicrobial drug resistance
beta-lactam resistance
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1519-69842023000100494&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1519-69842023000100494&tlng=en

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