Storage and Utilization of Glycogen by Mouse Liver during Adaptation to Nutritional Changes Are GLP-1 and PASK Dependent

Storage and Utilization of Glycogen by Mouse Liver during Adaptation to Nutritional Changes Are GLP-1 and PASK Dependent

Glucagon-like peptide 1 (GLP-1) and PAS kinase (PASK) control glucose and energy homeostasis according to nutritional status. Thus, both glucose availability and GLP-1 lead to hepatic glycogen synthesis or degradation. We used a murine model to discover whether PASK mediates the effect of exendin-4...

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Bibliographic Details
Main Authors: Ana Pérez-García, Verónica Hurtado-Carneiro, Carmen Herrero-De-Dios, Pilar Dongil, José Enrique García-Mauriño, María Dolores Sánchez, Carmen Sanz, Elvira Álvarez
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Nutrients
Subjects:
exendin-4
glucose
metabolic sensors
diabetes
glucokinase
fasting
Online Access:https://www.mdpi.com/2072-6643/13/8/2552

Internet

https://www.mdpi.com/2072-6643/13/8/2552

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