Enveloped viruses distinct from HBV induce dissemination of hepatitis D virus in vivo

Hepatitis D virus (HDV) relies on a helper virus to package and transmit its ribonucleoprotein (RNP). Here, Perez-Vargas et al. show that HDV can use envelope proteins from HBV-unrelated viruses, including HCV and flaviviruses, to propagate in vitro and in humanized mice.

Bibliographic Details
Main Authors: Jimena Perez-Vargas, Fouzia Amirache, Bertrand Boson, Chloé Mialon, Natalia Freitas, Camille Sureau, Floriane Fusil, François-Loïc Cosset
Format: Article
Language:English
Published: Nature Portfolio 2019-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-10117-z