ADAR1 promotes systemic sclerosis via modulating classic macrophage activation

ADAR1 promotes systemic sclerosis via modulating classic macrophage activation

IntroductionAs a multisystem autoimmune disorder disease, systemic sclerosis (SSc) is characterized by inflammation and fibrosis in the skin and other internal organs. However, mechanisms underlying the inflammatory response that drives the development of SSc remain largely unknown.MethodsADAR1 hete...

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Bibliographic Details
Main Authors: Chenming Sun, Dunpeng Cai, Shi-You Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Immunology
Subjects:
ADAR1
macrophage activation
systemic sclerosis
NF-κB
IL-1β
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1051254/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1051254/full

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