Circulating indian hedgehog is a marker of the hepatocyte-TAZ pathway in experimental NASH and is elevated in humans with NASH

Circulating indian hedgehog is a marker of the hepatocyte-TAZ pathway in experimental NASH and is elevated in humans with NASH

Background & Aims: Non-alcoholic steatohepatitis (NASH)-induced liver fibrosis is emerging as the most common cause of liver disease. For evaluation of therapies, there is a pressing need to identify non-invasive, mechanism-based biomarkers. A pro-fibrotic process relevant to human NASH invo...

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Bibliographic Details
Main Authors: Mary Patricia Moore, Xiaobo Wang, Hongxue Shi, Marica Meroni, Alessandro Cherubini, Luisa Ronzoni, Elizabeth J. Parks, Jamal A. Ibdah, R. Scott Rector, Luca Valenti, Paola Dongiovanni, Ira Tabas
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:JHEP Reports
Subjects:
NASH
NAFLD
Fibrosis
TAZ
IHH
Biomarker
Online Access:http://www.sciencedirect.com/science/article/pii/S2589555923000472

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http://www.sciencedirect.com/science/article/pii/S2589555923000472

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