The Effects of Thymoquinone on Viability, and Anti-apoptotic Factors (BCL-XL, BCL-2, MCL-1) in Prostate Cancer (PC3) Cells: An In Vitro and Computer-Simulated Environment Study

The Effects of Thymoquinone on Viability, and Anti-apoptotic Factors (BCL-XL, BCL-2, MCL-1) in Prostate Cancer (PC3) Cells: An In Vitro and Computer-Simulated Environment Study

Purpose: Since active plant ingredients can induce apoptosis in many tumors, in this study we evaluate the apoptotic effects of thymoquinone (TQ) on PC3 cells. Also, we predicted the interaction of TQ with BCL-XL, BCL-2, and MCL-1anti-apoptotic factors by computer-simulated environment. Methods: PC3...

Full description

Bibliographic Details
Main Authors: Javad Saffari_Chaleshtori, Ehsan Heidari-Sureshjani, Fahimeh Moradi, Esfandiar Heidarian
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2019-08-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
Thymoquinone
Apoptosis
Cancer
Simulation
Online Access:https://apb.tbzmed.ac.ir/PDF/apb-26457

Internet

https://apb.tbzmed.ac.ir/PDF/apb-26457

Similar Items