Consequences of Acute or Chronic Methylphenidate Exposure Using Ex Vivo Neurochemistry and In Vivo Electrophysiology in the Prefrontal Cortex and Striatum of Rats

Consequences of Acute or Chronic Methylphenidate Exposure Using Ex Vivo Neurochemistry and In Vivo Electrophysiology in the Prefrontal Cortex and Striatum of Rats

Methylphenidate (MPH) is among the main drugs prescribed to treat patients with attention-deficit and hyperactivity disease (ADHD). MPH blocks both the norepinephrine and dopamine reuptake transporters (NET and DAT, respectively). Our study was aimed at further understanding the mechanisms by which...

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Bibliographic Details
Main Authors: Mathieu Di Miceli, Asma Derf, Benjamin Gronier
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
ADHD
methylphenidate
neurotransmitter release
striatum
medium spiny neurons
pyramidal neurons
Online Access:https://www.mdpi.com/1422-0067/23/15/8588

Internet

https://www.mdpi.com/1422-0067/23/15/8588

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