Roles of JAK2 in Aging, Inflammation, Hematopoiesis and Malignant Transformation
Clonal alterations in hematopoietic cells occur during aging and are often associated with the establishment of a subclinical inflammatory environment. Several age-related conditions and diseases may be initiated or promoted by these alterations. JAK2 mutations are among the most frequently mutated...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-08-01
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Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/8/8/854 |