Roles of JAK2 in Aging, Inflammation, Hematopoiesis and Malignant Transformation

Clonal alterations in hematopoietic cells occur during aging and are often associated with the establishment of a subclinical inflammatory environment. Several age-related conditions and diseases may be initiated or promoted by these alterations. JAK2 mutations are among the most frequently mutated...

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Bibliographic Details
Main Authors: Florian Perner, Caroline Perner, Thomas Ernst, Florian H. Heidel
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/8/8/854