Functional Characterisation of the Circular RNA, <i>circHTT(2-6)</i>, in Huntington’s Disease

Functional Characterisation of the Circular RNA, <i>circHTT(2-6)</i>, in Huntington’s Disease

Trinucleotide repeat disorders comprise ~20 severe, inherited, human neuromuscular and neurodegenerative disorders, which result from an abnormal expansion of repetitive sequences in the DNA. The most common of these, Huntington’s disease (HD), results from expansion of the CAG repeat region in exon...

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Bibliographic Details
Main Authors: Laura Gantley, Brett W. Stringer, Vanessa M. Conn, Youichirou Ootsuka, Duncan Holds, Mark Slee, Kamelya Aliakbari, Kirsty Kirk, Rebecca J. Ormsby, Stuart T. Webb, Adrienne Hanson, He Lin, Luke A. Selth, Simon J. Conn
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Cells
Subjects:
circular RNA
Huntington’s disease
<i>Huntingtin</i>
<i>HTT</i>
triplet repeat disorders
Online Access:https://www.mdpi.com/2073-4409/12/9/1337

Internet

https://www.mdpi.com/2073-4409/12/9/1337

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