MELK promotes HCC carcinogenesis through modulating cuproptosis-related gene DLAT-mediated mitochondrial function
Abstract Cuproptosis caused by copper overload is mediated by a novel regulatory mechanism that differs from previously documented mechanisms regulating cell death. Cells dependent on mitochondrial respiration showed increased sensitivity to a copper ionophore elesclomol that induced cuproptosis. Ma...
Main Authors: | Zhipeng Li, Huaxin Zhou, Xiangyu Zhai, Lin Gao, Mengfan Yang, Baokun An, Tong Xia, Gang Du, Xiaoming Li, Wei Wang, Bin Jin |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2023-11-01
|
Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-023-06264-3 |
Similar Items
-
Correction: MELK promotes HCC carcinogenesis through modulating cuproptosis-related gene DLAT-mediated mitochondrial function
by: Zhipeng Li, et al.
Published: (2023-12-01) -
PM2.5 promotes NSCLC carcinogenesis through translationally and transcriptionally activating DLAT-mediated glycolysis reprograming
by: Qianqian Chen, et al.
Published: (2022-07-01) -
Comprehensive analysis identifies cuproptosis-related gene DLAT as a potential prognostic and immunological biomarker in pancreatic adenocarcinoma
by: Xiaoling Zhang, et al.
Published: (2023-06-01) -
Roles of cuproptosis-related gene DLAT in various cancers: a bioinformatic analysis and preliminary verification on pro-survival autophagy
by: Qinjing Yang, et al.
Published: (2023-03-01) -
Analysis of cuproptosis in hepatocellular carcinoma using multi-omics reveals a comprehensive HCC landscape and the immune patterns of cuproptosis
by: Xinqiang Li, et al.
Published: (2022-11-01)