Penaeus monodon Interferon Regulatory Factor (PmIRF) Activates IFNs and Antimicrobial Peptide Expression via a STING-Dependent DNA Sensing Pathway

Penaeus monodon Interferon Regulatory Factor (PmIRF) Activates IFNs and Antimicrobial Peptide Expression via a STING-Dependent DNA Sensing Pathway

Interferon regulatory factors (IRFs) are transcription factors found in both vertebrates and invertebrates that were recently identified and found to play an important role in antiviral immunity in black tiger shrimp Penaeus monodon. In this study, we investigated the mechanism by which P. monodon I...

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Bibliographic Details
Main Authors: Suthinee Soponpong, Piti Amparyup, Taro Kawai, Anchalee Tassanakajon
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Immunology
Subjects:
IRF
STING
DNA sensing pathway
antiviral response
interferon
shrimp immunity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.818267/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.818267/full

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