Optimization of protein removal process of Lonicera japonica polysaccharide and its immunomodulatory mechanism in cyclophosphamide‐induced mice by metabolomics and network pharmacology

Abstract In this study, TCA–n‐butanol was chosen as the best deproteinization method for Lonicera japonica polysaccharide (LJP) by comparing the polysaccharide retention rate and the protein clearance rate of five different methods. The response surface methodology (RSM) based on the Box–Behnken des...

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Bibliographic Details
Main Authors: Jie Ding, Haitao Du, Haining Tan, Jing Li, Lingna Wang, Li Li, Yongqing Zhang, Yuhong Liu
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Food Science & Nutrition
Subjects:
Online Access:https://doi.org/10.1002/fsn3.3067