Influence of splenectomy on the biodistribution of technetium-99m dimercaptosuccinic acid (99mTc-DMSA) in rats

This study aimed to evaluate if the splenectomy alters the biodistribution of 99mTc-DMSA and renal function in Wistar rats. The animals were separated in the groups: splenectomy (n = 6) and control (n = 6). After splenectomy (15 days), the administration of 0.1ml of 99mTc-DMSA IV (0.48 MBq) was carr...

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Main Authors: Maria Kadja Meneses Torres Açucena, Kércia Regina Santos Gomes Pereira, Arthur Villarim Neto, Amália Cínthia Meneses Rêgo, Mario Bernardo-Filho, Ítalo Medeiros Azevedo, Irami Araújo Filho, Aldo Cunha Medeiros
Format: Article
Language:English
Published: Instituto de Tecnologia do Paraná (Tecpar) 2008-12-01
Series:Brazilian Archives of Biology and Technology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132008000700032