Loss-of-function variants in KCTD19 cause non-obstructive azoospermia in humans

Loss-of-function variants in KCTD19 cause non-obstructive azoospermia in humans

Summary: Azoospermia is a significant cause of male infertility, with non-obstructive azoospermia (NOA) being the most severe type of spermatogenic failure. NOA is mostly caused by congenital factors, but our understanding of its genetic causes is very limited. Here, we identified a frameshift varia...

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Bibliographic Details
Main Authors: Junyan Liu, Fazal Rahim, Jianteng Zhou, Suixing Fan, Hanwei Jiang, Changping Yu, Jing Chen, Jianze Xu, Gang Yang, Wasim Shah, Muhammad Zubair, Asad Khan, Yang Li, Basit Shah, Daren Zhao, Furhan Iqbal, Xiaohua Jiang, Tonghang Guo, Peng Xu, Bo Xu, Limin Wu, Hui Ma, Yuanwei Zhang, Huan Zhang, Qinghua Shi
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:iScience
Subjects:
health sciences
biological sciences
Biochemistry
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223012701

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http://www.sciencedirect.com/science/article/pii/S2589004223012701

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