Intraprocedural endothelial cell seeding of arterial stents via biotin/avidin targeting mitigates in-stent restenosis

Abstract Impaired endothelialization of endovascular stents has been established as a major cause of in-stent restenosis and late stent thrombosis. Attempts to enhance endothelialization of inner stent surfaces by pre-seeding the stents with endothelial cells in vitro prior to implantation are compr...

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Bibliographic Details
Main Authors: Ivan S. Alferiev, Bahman Hooshdaran, Benjamin B. Pressly, Philip W. Zoltick, Stanley J. Stachelek, Michael Chorny, Robert J. Levy, Ilia Fishbein
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-23820-7