Development a novel robust method to enhance the solubility of Oxaprozin as nonsteroidal anti-inflammatory drug based on machine-learning

Abstract Accurate specification of the drugs’ solubility is known as an important activity to appropriately manage the supercritical impregnation process. Over the last decades, the application of supercritical fluids (SCFs), mainly CO2, has found great interest as a promising solution to dominate t...

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Bibliographic Details
Main Authors: Walid Kamal Abdelbasset, Safaa M. Elkholi, Khadiga Ahmed Ismail, Sameer Alshehri, Ahmed Alobaida, Bader Huwaimel, Ahmed D. Alatawi, Amal M. Alsubaiyel, Kumar Venkatesan, Mohammed A. S. Abourehab
Format: Article
Language:English
Published: Nature Portfolio 2022-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-17440-4