Sirt5 Inhibits BmNPV Replication by Promoting a Relish-Mediated Antiviral Pathway in Bombyx mori

Silent information regulators (Sirtuins) belong to the family of nicotinamide adenine dinucleotide (NAD+)-dependent histone deacetylases (HDACs) that have diverse functions in cells. Mammalian Sirtuins have seven isoforms (Sirt1–7) which have been found to play a role in viral replication. However,...

Full description

Bibliographic Details
Main Authors: Mengmeng Zhang, Shigang Fei, Junming Xia, Yeyuan Wang, Hongyun Wu, Xian Li, Yiyao Guo, Luc Swevers, Jingchen Sun, Min Feng
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.906738/full