CXCR4-BTK axis mediate pyroptosis and lipid peroxidation in early brain injury after subarachnoid hemorrhage via NLRP3 inflammasome and NF-κB pathway

CXCR4-BTK axis mediate pyroptosis and lipid peroxidation in early brain injury after subarachnoid hemorrhage via NLRP3 inflammasome and NF-κB pathway

C-X-C chemokine receptor type 4 (CXCR4) is critical for homeostasis of the adaptive and innate immune system in some CNS diseases. Bruton's tyrosine kinase (BTK) is an essential kinase that regulates inflammation in immune cells through multiple signaling pathways. This study aims to explore th...

Full description

Bibliographic Details
Main Authors: Chengli Liu, Kun Yao, Qi Tian, Yujia Guo, Guijun Wang, Peibang He, Jianfeng Wang, Jian Wang, Zhan Zhang, Mingchang Li
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Redox Biology
Subjects:
Subarachnoid hemorrhage
Neuroinflammation
Pyroptosis
BTK
CXCR4
Lipid peroxidation
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231723003610

Internet

http://www.sciencedirect.com/science/article/pii/S2213231723003610

Similar Items