Therapeutic response to leflunomide in combo therapy and monotherapy is associated to serum teriflunomide (A77 1726) levels

Therapeutic response to leflunomide in combo therapy and monotherapy is associated to serum teriflunomide (A77 1726) levels

Abstract There is a significant rate of therapeutic failure in rheumatoid arthritis (RA) patients treated with leflunomide (LEF). This study investigates the utility values of teriflunomide levels (A77 1726) in identifying RA patients who remained with moderate or severe disease activity after the t...

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Bibliographic Details
Main Authors: Nicte S. Fajardo-Robledo, Heriberto Jacobo-Cuevas, Edsaul E. Perez-Guerrero, Esther G. Corona-Sanchez, A. Miriam Saldaña-Cruz, Elba M. Romero-Tejeda, N. Alejandra Rodriguez-Jimenez, Sylvia E. Totsuka-Sutto, Rocio I. Lopez-Roa, Juan M. Ponce-Guarneros, M. Fabiola Alcaraz-Lopez, Sergio Cerpa-Cruz, J. Francisco Muñoz-Valle, E. German Cardona-Muñoz, Laura Gonzalez-Lopez, Jorge I. Gamez-Nava, Research Group for Factors Related to Therapeutic Outcomes in Autoimmune Diseases
Format: Article
Language:English
Published: Nature Portfolio 2022-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-05644-7

Internet

https://doi.org/10.1038/s41598-022-05644-7

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