Micro-CT Features of Lung Consolidation, Collagen Deposition and Inflammation in Experimental RSV Infection Are Aggravated in the Absence of Nrf2

Micro-CT Features of Lung Consolidation, Collagen Deposition and Inflammation in Experimental RSV Infection Are Aggravated in the Absence of Nrf2

Severe respiratory syncytial virus (RSV) infections in early life have been linked to the development of chronic airway disease. RSV triggers the production of reactive oxygen species (ROS), which contributes to inflammation and enhanced clinical disease. NF-E2-related factor 2 (Nrf2) is an importan...

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Bibliographic Details
Main Authors: Teodora Ivanciuc, Igor Patrikeev, Yue Qu, Massoud Motamedi, Yava Jones-Hall, Antonella Casola, Roberto P. Garofalo
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Viruses
Subjects:
respiratory syncytial virus
Nrf2
collagen
micro-CT
airway remodeling
Online Access:https://www.mdpi.com/1999-4915/15/5/1191

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https://www.mdpi.com/1999-4915/15/5/1191

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