Risk Factors in Serrated Pathway Lesions: N-Glycosylation Profile as a Potential Biomarker of Progression to Malignancy

Risk Factors in Serrated Pathway Lesions: N-Glycosylation Profile as a Potential Biomarker of Progression to Malignancy

Introduction: The serrated pathway contributes to interval colorectal cancers, highlighting the need for new biomarkers to assess lesion progression risk. The β1,6-GlcNAc branched N-glycans expression in CRC cells was associated with an invasive phenotype and with immune evasion. Therefore, this stu...

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Bibliographic Details
Main Authors: Henrique Fernandes-Mendes, Catarina M. Azevedo, Mónica Garrido, Carolina Lemos, Isabel Pedroto, Salomé S. Pinho, Ricardo Marcos-Pinto, Ângela Fernandes
Format: Article
Language:English
Published: Karger Publishers 2024-01-01
Series:GE: Portuguese Journal of Gastroenterology
Subjects:
colorectal cancer
serrated pathway
serrated lesions
n-glycosylation
β1,6-glcnac branched n-glycans
biomarker
Online Access:https://beta.karger.com/Article/FullText/535920

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