Analysis of genomic sequence motifs for deciphering transcription factor binding and transcriptional regulation in eukaryotic cells

Eukaryotic genomes contain a variety of structured patterns: repetitive elements, binding sites of DNA and RNA associated proteins, splice sites and so on. Often, these structured patterns can be formalized as motifs and described using a proper mathematical model such as position weight matrix and...

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Bibliographic Details
Main Author: Valentina eBoeva
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-02-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2016.00024/full