Opportunities and short-comings of the axolotl salamander heart as a model system of human single ventricle and excessive trabeculation

Abstract Few experimental model systems are available for the rare congenital heart diseases of double inlet left ventricle (DILV), a subgroup of univentricular hearts, and excessive trabeculation (ET), or noncompaction. Here, we explore the heart of the axolotl salamander (Ambystoma mexicanum, Shaw...

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Bibliographic Details
Main Authors: Sophie Meyer, Henrik Lauridsen, Kathrine Pedersen, Sofie Amalie Andersson, Pim van Ooij, Tineke Willems, Rolf M. F. Berger, Tjark Ebels, Bjarke Jensen
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-24442-9