Co‐delivery Nano System of MS‐275 and V‐9302 Induces Pyroptosis and Enhances Anti‐Tumor Immunity Against Uveal Melanoma

Co‐delivery Nano System of MS‐275 and V‐9302 Induces Pyroptosis and Enhances Anti‐Tumor Immunity Against Uveal Melanoma

Abstract In the treatment of uveal melanoma (UVM), histone deacetylase inhibitors (HDACi) have emerged as a promising epigenetic therapy. However, their clinical efficacy is hindered by the suboptimal pharmacokinetics and the strong self‐rescue of tumor cells. To overcome these limitations, reactive...

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Bibliographic Details
Main Authors: Hong Ren, Zhenkai Wu, Jia Tan, Hui Tao, Wangyuan Zou, Zheng Cao, Binyu Wen, Ziyi Cai, Jiaqi Du, Zhihong Deng
Format: Article
Language:English
Published: Wiley 2024-08-01
Series:Advanced Science
Subjects:
epigenetic therapy
immunotherapy
metabolic intervention
pyroptosis
uveal melanoma
Online Access:https://doi.org/10.1002/advs.202404375

Internet

https://doi.org/10.1002/advs.202404375

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