Uncoupling Proteins and Regulated Proton Leak in Mitochondria

Uncoupling Proteins and Regulated Proton Leak in Mitochondria

Higher concentration of protons in the mitochondrial intermembrane space compared to the matrix results in an electrochemical potential causing the back flux of protons to the matrix. This proton transport can take place through ATP synthase complex (leading to formation of ATP) or can occur via pro...

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Bibliographic Details
Main Authors: Afshan Ardalan, Matthew D. Smith, Masoud Jelokhani-Niaraki
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:International Journal of Molecular Sciences
Subjects:
mitochondrial carriers
uncoupling proteins
ADP/ATP carrier
membrane protein structure and function
regulation and mechanism of proton transport
membrane protein oligomerization
Online Access:https://www.mdpi.com/1422-0067/23/3/1528

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https://www.mdpi.com/1422-0067/23/3/1528

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