QbD based development of HPLC method for simultaneous quantification of Telmisartan and Hydrochlorothiazide impurities in tablets dosage form

QbD based development of HPLC method for simultaneous quantification of Telmisartan and Hydrochlorothiazide impurities in tablets dosage form

A simple reverse phase liquid chromatographic gradient method has been developed and validated for the simultaneous determination of specified & un-specified impurities of Telmisartan and Hydrochlorothiazide in combination oral solid dosage forms. The developed method is effective to separat...

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Bibliographic Details
Main Authors: Ashok K. Palakurthi, Thirupathi Dongala, Lakshmi Narasimha R. Katakam
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Practical Laboratory Medicine
Subjects:
Analytical quality by design
Design of experiments
Telmisartan
Hydrochlorothiazide
Solid dosage form
HPLC-UV
Online Access:http://www.sciencedirect.com/science/article/pii/S2352551719301477

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http://www.sciencedirect.com/science/article/pii/S2352551719301477

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