Integrative metabolomics and transcriptomics analysis reveals novel therapeutic vulnerabilities in lung cancer

Integrative metabolomics and transcriptomics analysis reveals novel therapeutic vulnerabilities in lung cancer

Abstract Background Non‐small cell lung cancer (NSCLC) comprises the majority (~85%) of all lung tumors, with lung adenocarcinoma (LUAD) and squamous cell carcinoma (LUSC) being the most frequently diagnosed histological subtypes. Multi‐modal omics profiling has been carried out in NSCLC, but no stu...

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Bibliographic Details
Main Authors: Jose Thaiparambil, Jianrong Dong, Sandra L. Grimm, Dimuthu Perera, Chandra Shekar R. Ambati, Vasanta Putluri, Matthew J. Robertson, Tajhal D. Patel, Brandon Mistretta, Preethi H. Gunaratne, Min P. Kim, Jason T. Yustein, Nagireddy Putluri, Cristian Coarfa, Randa El‐Zein
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Cancer Medicine
Subjects:
adenocarcinoma of lung
carcinoma, non‐small‐cell lung
carcinoma, squamous cell
drug repositioning
lung neoplasms
metabolomics
Online Access:https://doi.org/10.1002/cam4.4933

Internet

https://doi.org/10.1002/cam4.4933

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