Mast Cell Tryptase Promotes Airway Remodeling by Inducing Anti-Apoptotic and Cell Growth Properties in Human Alveolar and Bronchial Epithelial Cells

Mast Cell Tryptase Promotes Airway Remodeling by Inducing Anti-Apoptotic and Cell Growth Properties in Human Alveolar and Bronchial Epithelial Cells

Bronchial and alveolar remodeling and impaired epithelial function are characteristics of chronic respiratory diseases. In these patients, an increased number of mast cells (MCs) positive for serine proteases, tryptase and chymase, infiltrate the epithelium and alveolar parenchyma. However, little i...

Full description

Bibliographic Details
Main Authors: Frida Berlin, Sofia Mogren, Camilla Ly, Sangeetha Ramu, Morten Hvidtfeldt, Lena Uller, Celeste Porsbjerg, Cecilia K. Andersson
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Cells
Subjects:
mast cell
proteases
tryptase
bronchial epithelium
alveolar epithelium
growth factors
Online Access:https://www.mdpi.com/2073-4409/12/10/1439

Internet

https://www.mdpi.com/2073-4409/12/10/1439

Similar Items