HSPB1 as an RNA-binding protein mediates the pathological process of osteoarthritis

HSPB1 as an RNA-binding protein mediates the pathological process of osteoarthritis

Abstract Heat-shock protein beta1 (HSPB1) is a member of the small HSP family, downregulated in osteoarthritis (OA) chondrocytes and demonstrated the capacity to serve as an RNA-binding protein (RBP). This work aimed to explore the profile of HSPB1 bound RNA and reveal the potential regulation mecha...

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Bibliographic Details
Main Authors: Qiang Fu, Yi Li, Chunhua Shi
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Osteoarthritis
iRIP-seq
RNA-binding
EGFR
ARE
Online Access:https://doi.org/10.1186/s13018-024-04580-8

Internet

https://doi.org/10.1186/s13018-024-04580-8

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