Longer leukocyte telomere length is associated with smaller hippocampal volume among non-demented APOE ε3/ε3 subjects.

Telomere length shortens with cellular division, and leukocyte telomere length is used as a marker for systemic telomere length. The hippocampus hosts adult neurogenesis and is an important structure for episodic memory, and carriers of the apolipoprotein E ε4 allele exhibit higher hippocampal atrop...

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Main Authors: Mikael Wikgren, Thomas Karlsson, Johanna Lind, Therese Nilbrink, Johan Hultdin, Kristel Sleegers, Christine Van Broeckhoven, Göran Roos, Lars-Göran Nilsson, Lars Nyberg, Rolf Adolfsson, Karl-Fredrik Norrback
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22506016/pdf/?tool=EBI