Mitochondrial transcription factor A in RORγt+ lymphocytes regulate small intestine homeostasis and metabolism

RORγt is known to play critical roles in the regulation of a number of immune cell subsets. Here the authors implicate mitochondrial transcription factor A in the regulation of intestinal RORγt + lymphocyte homeostasis and metabolic control in a murine in vivo model.

Bibliographic Details
Main Authors: Zheng Fu, Joseph W. Dean, Lifeng Xiong, Michael W. Dougherty, Kristen N. Oliff, Zong-ming E. Chen, Christian Jobin, Timothy J. Garrett, Liang Zhou
Format: Article
Language:English
Published: Nature Portfolio 2021-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-24755-9