Biosafety studies of carrier cells infected with a replication-competent adenovirus introduced by IAI.3B promoter

Biosafety studies of carrier cells infected with a replication-competent adenovirus introduced by IAI.3B promoter

The use of carrier cells infected with oncolytic viruses in cancer gene therapy is an attractive method because it can overcome viral immunogenicity and induce tumor immunity and significant antitumor activity. To enable human clinical trials of this treatment, acute and chronic toxicity tests must...

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Bibliographic Details
Main Authors: Katsuyuki Hamada, Toshiro Shirakawa, Shuji Terao, Akinobu Gotoh, Kenzaburo Tani, Wenlin Huang
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Molecular Therapy: Methods & Clinical Development
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050116300845

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http://www.sciencedirect.com/science/article/pii/S2329050116300845

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