A Caveat When Using Alkyl Halides as Tagging Agents to Detect/Quantify Reactive Sulfur Species

Using alkyl halides to tag reactive sulfur species (RSSs) (H<sub>2</sub>S, per/polysulfide, and protein-SSH) is an extensively applied approach. The underlying supposition is that, as with thiols, RSS reacts with alkyl halides via a nucleophilic substitution reaction. We found that this...

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Bibliographic Details
Main Authors: Xiaohua Wu, Yuping Xin, Qingda Wang, Yongzhen Xia, Luying Xun, Huaiwei Liu
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/11/8/1583