Imaging of viral neuroinvasion in the zebrafish reveals that Sindbis and chikungunya viruses favour different entry routes

Imaging of viral neuroinvasion in the zebrafish reveals that Sindbis and chikungunya viruses favour different entry routes

Alphaviruses, such as chikungunya virus (CHIKV) and Sindbis virus (SINV), are vector-borne pathogens that cause acute illnesses in humans and are sometimes associated with neuropathies, especially in infants and elderly patients. Little is known about their mechanism of entry into the central nervou...

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Bibliographic Details
Main Authors: Gabriella Passoni, Christelle Langevin, Nuno Palha, Bryan C. Mounce, Valérie Briolat, Pierre Affaticati, Elodie De Job, Jean-Stéphane Joly, Marco Vignuzzi, Maria-Carla Saleh, Philippe Herbomel, Pierre Boudinot, Jean-Pierre Levraud
Format: Article
Language:English
Published: The Company of Biologists 2017-07-01
Series:Disease Models & Mechanisms
Subjects:
Alphavirus
Chikungunya
Central nervous system
Zebrafish
Viral encephalitis
Live imaging
Online Access:http://dmm.biologists.org/content/10/7/847

Internet

http://dmm.biologists.org/content/10/7/847

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