Neuronal chemokine concentration gradients mediate effects of embryonic ethanol exposure on ectopic hypocretin/orexin neurons and behavior in zebrafish

Abstract Embryonic ethanol exposure in zebrafish and rats, while stimulating hypothalamic hypocretin/orexin (Hcrt) neurons along with alcohol consumption and related behaviors, increases the chemokine receptor Cxcr4 that promotes neuronal migration and may mediate ethanol’s effects on neuronal devel...

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Bibliographic Details
Main Authors: Adam D. Collier, Nushrat Yasmin, Olga Karatayev, Abdul R. Abdulai, Boyi Yu, Nailya Khalizova, Milisia Fam, Sarah F. Leibowitz
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-28369-7