Decoding the role of TET family dioxygenases in lineage specification

Abstract Since the discovery of methylcytosine oxidase ten-eleven translocation (TET) proteins, we have witnessed an exponential increase in studies examining their roles in epigenetic regulation. TET family proteins catalyze the sequential oxidation of 5-methylcytosine (5mC) to oxidized methylcytos...

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Bibliographic Details
Main Authors: Xinwei Wu, Gang Li, Ruiyu Xie
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Epigenetics & Chromatin
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13072-018-0228-7