Anti-CD3 Antibody Treatment Reduces Scar Formation in a Rat Model of Myocardial Infarction

Anti-CD3 Antibody Treatment Reduces Scar Formation in a Rat Model of Myocardial Infarction

Introduction: Antibody treatment with anti-thymocyte globulin (ATG) has been shown to be cardioprotective. We aimed to evaluate which single anti-T-cell epitope antibody alters chemokine expression at a level similar to ATG and identified CD3, which is a T-cell co-receptor mediating T-cell activatio...

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Bibliographic Details
Main Authors: Bernhard Wernly, Vera Paar, Achim Aigner, Patrick M Pilz, Bruno K Podesser, Martin Förster, Christian Jung, Josefina Pinon Hofbauer, Birgit Tockner, Monika Wimmer, Theo Kraus, Lukas J Motloch, Matthias Hackl, Uta C Hoppe, Attila Kiss, Michael Lichtenauer
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Cells
Subjects:
myocardial infarction
cd3
anti-cd
antibody treatment
cardioprotection
ami
apoptosis
angiogenesis
mirna
Online Access:https://www.mdpi.com/2073-4409/9/2/295

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https://www.mdpi.com/2073-4409/9/2/295

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