Only Acute but Not Chronic Thrombocytopenia Protects Mice against Left Ventricular Dysfunction after Acute Myocardial Infarction

Only Acute but Not Chronic Thrombocytopenia Protects Mice against Left Ventricular Dysfunction after Acute Myocardial Infarction

Background: Platelets are major players of thrombosis and inflammation after acute myocardial infarction (AMI). The impact of thrombocytopenia on platelet-induced cellular processes post AMI is not well defined. Methods: The left anterior descending artery was ligated in C57/Bl6 mice and in two thro...

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Bibliographic Details
Main Authors: Friedrich Reusswig, Amin Polzin, Meike Klier, Matthias Achim Dille, Aysel Ayhan, Marcel Benkhoff, Celina Lersch, Anika Prinz, Simone Gorressen, Jens Walter Fischer, Malte Kelm, Margitta Elvers
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Cells
Subjects:
platelets
myocardial infarction
inflammation
remodeling
scar formation
Online Access:https://www.mdpi.com/2073-4409/11/21/3500

Internet

https://www.mdpi.com/2073-4409/11/21/3500

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