Structural and Functional Insights into α-Synuclein Fibril Polymorphism

Structural and Functional Insights into α-Synuclein Fibril Polymorphism

Abnormal accumulation of aggregated α-synuclein (α-Syn) is seen in a variety of neurodegenerative diseases, including Parkinson’s disease (PD), multiple system atrophy (MSA), dementia with Lewy body (DLB), Parkinson’s disease dementia (PDD), and even subsets of Alzheimer’s disease (AD) showing Lewy-...

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Bibliographic Details
Main Authors: Surabhi Mehra, Laxmikant Gadhe, Riya Bera, Ajay Singh Sawner, Samir K. Maji
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Biomolecules
Subjects:
α-synuclein
amyloid
polymorphs
synucleinopathies
Online Access:https://www.mdpi.com/2218-273X/11/10/1419

Internet

https://www.mdpi.com/2218-273X/11/10/1419

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