Rescue of Low-Yield DNA Samples for Next-Generation Sequencing Using Vacuum Centrifugal Concentration in a Clinical Workflow

Rescue of Low-Yield DNA Samples for Next-Generation Sequencing Using Vacuum Centrifugal Concentration in a Clinical Workflow

The implementation of next-generation sequencing (NGS) in clinical oncology has enabled the analysis of multiple cancer-associated genes for diagnostics and treatment purposes. The detection of pathogenic and likely pathogenic mutations is crucial to manage the disease. Obtaining the mutational prof...

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Bibliographic Details
Main Authors: Lau K. Vestergaard, Nicolai S. Mikkelsen, Douglas V. N. P. Oliveira, Tim S. Poulsen, Estrid V. Hoegdall
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Reports
Subjects:
vacuum centrifugation
low-yield DNA
linear regression models
next-generation sequencing
cancer
targeted therapeutics
Online Access:https://www.mdpi.com/2571-841X/6/2/23

Internet

https://www.mdpi.com/2571-841X/6/2/23

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