Metoprolol Inhibits Developmental Brain Sterol Biosynthesis in Mice
De novo sterol synthesis is a critical homeostatic mechanism in the brain that begins during early embryonic development and continues throughout life. Multiple medications have sterol-biosynthesis-inhibiting side effects, with potentially detrimental effects on brain health. Using LC-MS/MS, we inve...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-08-01
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Series: | Biomolecules |
Subjects: | |
Online Access: | https://www.mdpi.com/2218-273X/12/9/1211 |