Exercise alters the circadian rhythm of REV-ERB-α and downregulates autophagy-related genes in peripheral and central tissues

Exercise alters the circadian rhythm of REV-ERB-α and downregulates autophagy-related genes in peripheral and central tissues

Abstract The transcriptional repressor REV-ERB-α, encoded by Nuclear Receptor Subfamily 1 Group D Member 1 (Nr1d1), has been considered to play an essential role in the skeletal muscle oxidative capacity adaptation and muscle mass control. Also, this molecule regulates autophagy via the repression o...

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Bibliographic Details
Main Authors: Alisson L. da Rocha, Ana P. Pinto, Bruno L. S. Bedo, Gustavo P. Morais, Luciana C. Oliveira, Ruither O. G. Carolino, Jose R. Pauli, Fernando M. Simabuco, Leandro P. de Moura, Eduardo R. Ropelle, Dennys E. Cintra, Donato A. Rivas, Adelino S. R. da Silva
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-24277-4

Internet

https://doi.org/10.1038/s41598-022-24277-4

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