Pervasive isoform‐specific translational regulation via alternative transcription start sites in mammals

Abstract Transcription initiated at alternative sites can produce mRNA isoforms with different 5ʹUTRs, which are potentially subjected to differential translational regulation. However, the prevalence of such isoform‐specific translational control across mammalian genomes is currently unknown. By co...

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Bibliographic Details
Main Authors: Xi Wang, Jingyi Hou, Claudia Quedenau, Wei Chen
Format: Article
Language:English
Published: Springer Nature 2016-07-01
Series:Molecular Systems Biology
Subjects:
Online Access:https://doi.org/10.15252/msb.20166941