SUN11602, a bFGF mimetic, modulated neuroinflammation, apoptosis and calcium-binding proteins in an in vivo model of MPTP-induced nigrostriatal degeneration

SUN11602, a bFGF mimetic, modulated neuroinflammation, apoptosis and calcium-binding proteins in an in vivo model of MPTP-induced nigrostriatal degeneration

Abstract Background Parkinson’s disease (PD) is the second most frequent neurodegenerative disease. PD etiopathogenesis is multifactorial and not yet fully known, however, the scientific world advised the establishment of neuroinflammation among the possible risk factors. In this field, basic fibrob...

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Bibliographic Details
Main Authors: Alessio Ardizzone, Valentina Bova, Giovanna Casili, Alessia Filippone, Michela Campolo, Marika Lanza, Emanuela Esposito, Irene Paterniti
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Journal of Neuroinflammation
Subjects:
Parkinson’s disease (PD)
SUN11602
MPTP-mouse model
Neuroprotective
Calbindin
Ca2+ homeostasis
Online Access:https://doi.org/10.1186/s12974-022-02457-3

Internet

https://doi.org/10.1186/s12974-022-02457-3

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