Rapamycin Suppresses Penile NADPH Oxidase Activity to Preserve Erectile Function in Mice Fed a Western Diet

Rapamycin Suppresses Penile NADPH Oxidase Activity to Preserve Erectile Function in Mice Fed a Western Diet

The mechanistic target of rapamycin (mTOR) is a nutrient-sensitive cellular signaling kinase that has been implicated in the excess production of reactive oxygen species (ROS). NADPH oxidase-derived ROS have been implicated in erectile dysfunction pathogenesis. The objective of this study was to det...

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Bibliographic Details
Main Authors: Justin D. La Favor, Clifford J. Pierre, Trinity J. Bivalacqua, Arthur L. Burnett
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Biomedicines
Subjects:
erectile dysfunction
Nox2
mTOR
p70S6K
microdialysis
high-fat
Online Access:https://www.mdpi.com/2227-9059/10/1/68

Internet

https://www.mdpi.com/2227-9059/10/1/68

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