An Episomal CRISPR/Cas12a System for Mediating Efficient Gene Editing

(1) Background: Gene editing technology, as represented by CRISPR is a powerful tool used in biomedical science. However, the editing efficiency of such technologies, especially in induced pluripotent stem cells (iPSCs) and other types of stem cells, is low which hinders its application in regenerat...

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Bibliographic Details
Main Authors: Nannan Duan, Shuqing Tang, Baitao Zeng, Zhiqing Hu, Qian Hu, Lingqian Wu, Miaojin Zhou, Desheng Liang
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/11/11/1262