Synthesis of 3-(2-Alkylthio-4-chloro-5-methylbenzenesulfonyl)-2-(1-phenyl-3-arylprop-2-enylideneamino)guanidine Derivatives with Pro-Apoptotic Activity against Cancer Cells

Synthesis of 3-(2-Alkylthio-4-chloro-5-methylbenzenesulfonyl)-2-(1-phenyl-3-arylprop-2-enylideneamino)guanidine Derivatives with Pro-Apoptotic Activity against Cancer Cells

The untypical course of reaction between chalcones and benzenesulfonylaminoguanidines led to the new 3-(2-alkylthio-4-chloro-5-methylbenzenesulfonyl)-2-(1-phenyl-3-arylprop-2-enylideneamino)guanidine derivatives <b>8</b>–<b>33</b>. The new compounds were tested in vitro for t...

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Bibliographic Details
Main Authors: Aneta Pogorzelska, Jarosław Sławiński, Anna Kawiak, Grzegorz Stasiłojć, Jarosław Chojnacki
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:International Journal of Molecular Sciences
Subjects:
benzenesulfonamides
benzenesulfonylguanidines
amidrazones
anticancer activity
cytotoxicity
cell cycle flow cytometry analysis
Online Access:https://www.mdpi.com/1422-0067/24/5/4436

Internet

https://www.mdpi.com/1422-0067/24/5/4436

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